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Leveraging Neuroscience-Informed Centrality for Topology-Aware Pruning in Neural Networks

Leveraging Neuroscience-Informed Centrality for Topology-Aware Pruning in Neural Networks

December 1, 2025

Inspired by the critical brain hypothesis in neuroscience, this paper explores and leverages centrality metrics to facilitate efficient pruning in deep neural networks. We develop a novel pruning meth...

Accepted to Efficient Large Vision Models @ CVPR 2025

Authors: Nick Cui, Trevor Xing-Xie, Arushi Gupta, Peter Choi

Inspired by the critical brain hypothesis in neuroscience, this paper explores and leverages centrality metrics to facilitate efficient pruning in deep neural networks. We develop a novel pruning methodology that uses neuroscience-informed centrality measures to identify and retain critical connections while removing redundant pathways. Our approach achieves competitive compression rates while maintaining model accuracy, demonstrating that biological principles can inform more efficient artificial neural network design. [arXiv link TBA]

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